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Oral high dose ascorbic acid treatment for one year in young CMT1A patients: a randomised, double-blind, placebo-controlled phase II trial

BACKGROUND: High dose oral ascorbic acid substantially improved myelination and locomotor function in a Charcot-Marie-Tooth type 1A mouse model. A phase II study was warranted to investigate whether high dose ascorbic acid also has such a substantial effect on myelination in Charcot-Marie-Tooth type...

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Detalles Bibliográficos
Autores principales:	Verhamme, Camiel, de Haan, Rob J, Vermeulen, Marinus, Baas, Frank, de Visser, Marianne, van Schaik, Ivo N
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784478/ https://www.ncbi.nlm.nih.gov/pubmed/19909499 http://dx.doi.org/10.1186/1741-7015-7-70

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