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HIV-1 evades virus-specific IgG2 and IgA class switching by targeting systemic and intestinal B cells via long-range intercellular conduits

Contact-dependent communication between immune cells generates protection, but also facilitates viral spread. We found that macrophages formed long-range actin-propelled conduits in response to negative factor (Nef), a human immunodeficiency virus type-1 (HIV-1) protein with immunosuppressive functi...

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Detalles Bibliográficos
Autores principales: Xu, Weifeng, Santini, Paul A., Sullivan, John S., He, Bing, Shan, Meimei, Ball, Susan C., Dyer, Wayne B., Ketas, Thomas J., Chadburn, Amy, Cohen-Gould, Leona, Knowles, Daniel M., Chiu, April, Sanders, Rogier W., Chen, Kang, Cerutti, Andrea
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784687/
https://www.ncbi.nlm.nih.gov/pubmed/19648924
http://dx.doi.org/10.1038/ni.1753