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The expression of Gli3, regulated by HOXD13, may play a role in idiopathic congenital talipes equinovarus

BACKGROUND: Idiopathic congenital talipes equinovarus (ICTEV) is a congenital limb deformity. Based on extended transmission disequilibrium testing, Gli-Kruppel family member 3 (Gli3) has been identified as a candidate gene for ICTEV. Here, we verify the role of Gli3 in ICTEV development. METHODS: U...

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Detalles Bibliográficos
Autores principales: Cao, DongHua, Jin, ChunLian, Ren, MeiHong, Lin, ChangKun, Zhang, Xuan, Zhao, Ning
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784749/
https://www.ncbi.nlm.nih.gov/pubmed/19925654
http://dx.doi.org/10.1186/1471-2474-10-142