The unfolded protein response and its relevance to connective tissue diseases

The unfolded protein response (UPR) has evolved to counter the stresses that occur in the endoplasmic reticulum (ER) as a result of misfolded proteins. This sophisticated quality control system attempts to restore homeostasis through the action of a number of different pathways that are coordinated...

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Detalles Bibliográficos
Autores principales: Boot-Handford, Raymond P., Briggs, Michael D.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784867/
https://www.ncbi.nlm.nih.gov/pubmed/19851784
http://dx.doi.org/10.1007/s00441-009-0877-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784867/
https://www.ncbi.nlm.nih.gov/pubmed/19851784
http://dx.doi.org/10.1007/s00441-009-0877-8

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