Predicting Functional Alternative Splicing by Measuring RNA Selection Pressure from Multigenome Alignments

High-throughput methods such as EST sequencing, microarrays and deep sequencing have identified large numbers of alternative splicing (AS) events, but studies have shown that only a subset of these may be functional. Here we report a sensitive bioinformatics approach that identifies exons with evide...

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Detalles Bibliográficos
Autores principales: Lu, Hongchao, Lin, Lan, Sato, Seiko, Xing, Yi, Lee, Christopher J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784930/
https://www.ncbi.nlm.nih.gov/pubmed/20019791
http://dx.doi.org/10.1371/journal.pcbi.1000608

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784930/
https://www.ncbi.nlm.nih.gov/pubmed/20019791
http://dx.doi.org/10.1371/journal.pcbi.1000608

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