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Predicting Functional Alternative Splicing by Measuring RNA Selection Pressure from Multigenome Alignments
High-throughput methods such as EST sequencing, microarrays and deep sequencing have identified large numbers of alternative splicing (AS) events, but studies have shown that only a subset of these may be functional. Here we report a sensitive bioinformatics approach that identifies exons with evide...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784930/ https://www.ncbi.nlm.nih.gov/pubmed/20019791 http://dx.doi.org/10.1371/journal.pcbi.1000608 |