Extramitochondrial Ca(2+) in the Nanomolar Range Regulates Glutamate-Dependent Oxidative Phosphorylation on Demand

We present unexpected and novel results revealing that glutamate-dependent oxidative phosphorylation (OXPHOS) of brain mitochondria is exclusively and efficiently activated by extramitochondrial Ca(2+) in physiological concentration ranges (S(0.5) = 360 nM Ca(2+)). This regulation was not affected b...

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Detalles Bibliográficos
Autores principales: Gellerich, Frank Norbert, Gizatullina, Zemfira, Arandarcikaite, Odeta, Jerzembek, Doreen, Vielhaber, Stefan, Seppet, Enn, Striggow, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784944/
https://www.ncbi.nlm.nih.gov/pubmed/20011041
http://dx.doi.org/10.1371/journal.pone.0008181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784944/
https://www.ncbi.nlm.nih.gov/pubmed/20011041
http://dx.doi.org/10.1371/journal.pone.0008181

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