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Extramitochondrial Ca(2+) in the Nanomolar Range Regulates Glutamate-Dependent Oxidative Phosphorylation on Demand
We present unexpected and novel results revealing that glutamate-dependent oxidative phosphorylation (OXPHOS) of brain mitochondria is exclusively and efficiently activated by extramitochondrial Ca(2+) in physiological concentration ranges (S(0.5) = 360 nM Ca(2+)). This regulation was not affected b...
Autores principales: | Gellerich, Frank Norbert, Gizatullina, Zemfira, Arandarcikaite, Odeta, Jerzembek, Doreen, Vielhaber, Stefan, Seppet, Enn, Striggow, Frank |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784944/ https://www.ncbi.nlm.nih.gov/pubmed/20011041 http://dx.doi.org/10.1371/journal.pone.0008181 |
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