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Functional Memory B Cells and Long-Lived Plasma Cells Are Generated after a Single Plasmodium chabaudi Infection in Mice

Antibodies have long been shown to play a critical role in naturally acquired immunity to malaria, but it has been suggested that Plasmodium-specific antibodies in humans may not be long lived. The cellular mechanisms underlying B cell and antibody responses are difficult to study in human infection...

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Detalles Bibliográficos
Autores principales: Ndungu, Francis Maina, Cadman, Emma Tamsin, Coulcher, Joshua, Nduati, Eunice, Couper, Elisabeth, MacDonald, Douglas William, Ng, Dorothy, Langhorne, Jean
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784955/
https://www.ncbi.nlm.nih.gov/pubmed/20011127
http://dx.doi.org/10.1371/journal.ppat.1000690