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Altered Synthesis of Cartilage-Specific Proteoglycans by Mutant Human Cartilage Oligomeric Matrix Protein

BACKGROUND: The mechanism by which mutant cartilage oligomeric matrix protein (COMP) induces a pseudoachondroplasia phenotype remains unknown, and the reason why a mutation of a minor protein of the growth plate cartilage causes total disruption of endochondral bone formation has not yet been determ...

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Detalles Bibliográficos
Autores principales: Kwak, Yoon Hae, Roh, Jae Young, Lee, Ki Seok, Park, Hui Wan, Kim, Hyun Woo
Formato: Texto
Lenguaje:English
Publicado: The Korean Orthopaedic Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784957/
https://www.ncbi.nlm.nih.gov/pubmed/19956474
http://dx.doi.org/10.4055/cios.2009.1.4.181