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Immunization of Mice with a Recombinant Adenovirus Vaccine Inhibits the Early Growth of Mycobacterium tuberculosis After Infection

BACKGROUND: In pulmonary Mycobacterium tuberculosis (Mtb) infection, immune responses are delayed compared to other respiratory infections, so that antigen-specific cells are not detected in the lungs earlier than day 14. Even after parenteral immunization with Bacille Calmette Guerin (BCG) or a sub...

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Detalles Bibliográficos
Autores principales: Ronan, Edward O., Lee, Lian Ni, Beverley, Peter C. L., Tchilian, Elma Z.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785469/
https://www.ncbi.nlm.nih.gov/pubmed/20011050
http://dx.doi.org/10.1371/journal.pone.0008235