The Immunogenic SigA Enterotoxin of Shigella flexneri 2a Binds to HEp-2 Cells and Induces Fodrin Redistribution in Intoxicated Epithelial Cells

BACKGROUND: We have previously shown that the enterotoxin SigA which resides on the she pathogenicity island (PAI) of S. flexneri 2a is an autonomously secreted serine protease capable of degrading casein. We have also demonstrated that SigA is cytopathic for HEp-2 cells and plays a role in the inte...

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Detalles Bibliográficos
Autores principales: Al-Hasani, Keith, Navarro-Garcia, Fernando, Huerta, Jazmin, Sakellaris, Harry, Adler, Ben
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785471/
https://www.ncbi.nlm.nih.gov/pubmed/20011051
http://dx.doi.org/10.1371/journal.pone.0008223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785471/
https://www.ncbi.nlm.nih.gov/pubmed/20011051
http://dx.doi.org/10.1371/journal.pone.0008223

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