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In vivo administration of BL-3050: highly stable engineered PON1-HDL complexes

BACKGROUND: Serum paraoxonase (PON1) is a high density lipoprotein (HDL)-associated enzyme involved in organophosphate (OP) degradation and prevention of atherosclerosis. PON1 comprises a potential candidate for in vivo therapeutics, as an anti-atherogenic agent, and for detoxification of pesticides...

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Detalles Bibliográficos
Autores principales: Gaidukov, Leonid, Bar, Dganit, Yacobson, Shiri, Naftali, Esmira, Kaufman, Olga, Tabakman, Rinat, Tawfik, Dan S, Levy-Nissenbaum, Etgar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785756/
https://www.ncbi.nlm.nih.gov/pubmed/19922610
http://dx.doi.org/10.1186/1472-6904-9-18