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Oxaliplatin-induced loss of phosphorylated heavy neurofilament subunit neuronal immunoreactivity in rat DRG tissue

BACKGROUND: Oxaliplatin and related chemotherapeutic drugs cause painful chronic peripheral neuropathies in cancer patients. We investigated changes in neuronal size profiles and neurofilament immunoreactivity in L5 dorsal root ganglion (DRG) tissue of adult female Wistar rats after multiple-dose tr...

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Detalles Bibliográficos
Autores principales: Jamieson, Stephen MF, Subramaniam, Joshuan, Liu, Johnson J, Jong, Nancy N, Ip, Virginia, Connor, Bronwen, McKeage, Mark J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785764/
https://www.ncbi.nlm.nih.gov/pubmed/19922644
http://dx.doi.org/10.1186/1744-8069-5-66