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Conditional gene deletion reveals functional redundancy of GABA(B )receptors in peripheral nociceptors in vivo

BACKGROUND: γ-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly mediates its effects on neurons via ionotropic (GABA(A)) and metabotropic (GABA(B)) receptors. GABA(B )receptors are widely expressed in the central and the peripheral nervous system. Although there is ev...

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Detalles Bibliográficos
Autores principales: Gangadharan, Vijayan, Agarwal, Nitin, Brugger, Stefan, Tegeder, Imgard, Bettler, Bernhard, Kuner, Rohini, Kurejova, Martina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785766/
https://www.ncbi.nlm.nih.gov/pubmed/19925671
http://dx.doi.org/10.1186/1744-8069-5-68