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Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis

BACKGROUND: Therapeutic strategies exist for human pulmonary neoplasia, however due to the heterogeneity of the disease, most are not very effective. The innate immunity gene, toll-like receptor 4 (TLR4), protects against chronic pulmonary inflammation and tumorigenesis in mice, but the mechanism is...

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Detalles Bibliográficos
Autores principales: Bauer, Alison K, Fostel, Jennifer, Degraff, Laura M, Rondini, Elizabeth A, Walker, Christopher, Grissom, Sherry F, Foley, Julie, Kleeberger, Steven R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785769/
https://www.ncbi.nlm.nih.gov/pubmed/19925653
http://dx.doi.org/10.1186/1476-4598-8-107