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Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis
BACKGROUND: Therapeutic strategies exist for human pulmonary neoplasia, however due to the heterogeneity of the disease, most are not very effective. The innate immunity gene, toll-like receptor 4 (TLR4), protects against chronic pulmonary inflammation and tumorigenesis in mice, but the mechanism is...
Autores principales: | Bauer, Alison K, Fostel, Jennifer, Degraff, Laura M, Rondini, Elizabeth A, Walker, Christopher, Grissom, Sherry F, Foley, Julie, Kleeberger, Steven R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785769/ https://www.ncbi.nlm.nih.gov/pubmed/19925653 http://dx.doi.org/10.1186/1476-4598-8-107 |
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