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Abnormalities in brain structure and behavior in GSK-3alpha mutant mice

BACKGROUND: Glycogen synthase kinase-3 (GSK-3) is a widely expressed and highly conserved serine/threonine protein kinase encoded by two genes that generate two related proteins: GSK-3α and GSK-3β. Mice lacking a functional GSK-3α gene were engineered in our laboratory; they are viable and display i...

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Detalles Bibliográficos
Autores principales: Kaidanovich-Beilin, Oksana, Lipina, Tatiana V, Takao, Keizo, van Eede, Matthijs, Hattori, Satoko, Laliberté, Christine, Khan, Mustafa, Okamoto, Kenichi, Chambers, John W, Fletcher, Paul J, MacAulay, Katrina, Doble, Bradley W, Henkelman, Mark, Miyakawa, Tsuyoshi, Roder, John, Woodgett, James R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785804/
https://www.ncbi.nlm.nih.gov/pubmed/19925672
http://dx.doi.org/10.1186/1756-6606-2-35