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Abnormalities in brain structure and behavior in GSK-3alpha mutant mice
BACKGROUND: Glycogen synthase kinase-3 (GSK-3) is a widely expressed and highly conserved serine/threonine protein kinase encoded by two genes that generate two related proteins: GSK-3α and GSK-3β. Mice lacking a functional GSK-3α gene were engineered in our laboratory; they are viable and display i...
Autores principales: | Kaidanovich-Beilin, Oksana, Lipina, Tatiana V, Takao, Keizo, van Eede, Matthijs, Hattori, Satoko, Laliberté, Christine, Khan, Mustafa, Okamoto, Kenichi, Chambers, John W, Fletcher, Paul J, MacAulay, Katrina, Doble, Bradley W, Henkelman, Mark, Miyakawa, Tsuyoshi, Roder, John, Woodgett, James R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785804/ https://www.ncbi.nlm.nih.gov/pubmed/19925672 http://dx.doi.org/10.1186/1756-6606-2-35 |
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