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P38 MAP Kinase inhibition promotes primary tumour growth via VEGF independent mechanism

BACKGROUND: The surgical insult induces an inflammatory response that activates P38 MAP kinases and solid tumours can also release cytokines. Therfore inhibition of these pathways may reduce tumour growth We set out to examine the effects of P38-MAPK inhibition on apoptosis, proliferation, VEGF rele...

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Detalles Bibliográficos
Autores principales: O'Sullivan, Adrian W, Wang, Jiang H, Redmond, Henry P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785811/
https://www.ncbi.nlm.nih.gov/pubmed/19912664
http://dx.doi.org/10.1186/1477-7819-7-89