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Enhanced ERbeta immunoexpression and apoptosis in the germ cells of cimetidine-treated rats

BACKGROUND: Cimetidine, refereed as antiandrogenic drug, causes hormonal changes in male patients such as increased testosterone and FSH levels. In the rat testis, structural alterations in the seminiferous tubules have been related to germ cell loss and Sertoli cell death by apoptosis. Regarding th...

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Detalles Bibliográficos
Autor principal: Sasso-Cerri, Estela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785817/
https://www.ncbi.nlm.nih.gov/pubmed/19922658
http://dx.doi.org/10.1186/1477-7827-7-127