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Enhanced ERbeta immunoexpression and apoptosis in the germ cells of cimetidine-treated rats
BACKGROUND: Cimetidine, refereed as antiandrogenic drug, causes hormonal changes in male patients such as increased testosterone and FSH levels. In the rat testis, structural alterations in the seminiferous tubules have been related to germ cell loss and Sertoli cell death by apoptosis. Regarding th...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785817/ https://www.ncbi.nlm.nih.gov/pubmed/19922658 http://dx.doi.org/10.1186/1477-7827-7-127 |