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DNA-AP sites generation by Etoposide in whole blood cells

BACKGROUND: Etoposide is currently one of the most commonly used antitumor drugs. The mechanisms of action proposed for its antitumor activity are based mainly on its interaction with topoisomerase II. Etoposide effects in transformed cells have been described previously. The aim of the present stud...

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Detalles Bibliográficos
Autores principales: Rojas, Emilio, Mussali, Patricia, Tovar, Efrain, Valverde, Mahara
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785836/
https://www.ncbi.nlm.nih.gov/pubmed/19917085
http://dx.doi.org/10.1186/1471-2407-9-398