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Alu repeats increase local recombination rates

BACKGROUND: Recombination rates vary widely across the human genome, but little of that variation is correlated with known DNA sequence features. The genome contains more than one million Alu mobile element insertions, and these insertions have been implicated in non-homologous recombination, modula...

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Detalles Bibliográficos
Autores principales: Witherspoon, David J, Watkins, W Scott, Zhang, Yuhua, Xing, Jinchuan, Tolpinrud, Whitney L, Hedges, Dale J, Batzer, Mark A, Jorde, Lynn B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785838/
https://www.ncbi.nlm.nih.gov/pubmed/19917129
http://dx.doi.org/10.1186/1471-2164-10-530