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Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells
BACKGROUND: Sharing a common ErbB/HER receptor signaling pathway, heregulin (HRG) induces differentiation of MCF-7 human breast cancer cells while epidermal growth factor (EGF) elicits proliferation. Although cell fates resulting from action of the aforementioned ligands completely different, the re...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785842/ https://www.ncbi.nlm.nih.gov/pubmed/19925682 http://dx.doi.org/10.1186/1471-2164-10-545 |