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Sensation and Signaling of α-Ketoglutarate and Adenylylate Energy Charge by the Escherichia coli PII Signal Transduction Protein Require Cooperation of the Three Ligand-Binding Sites within the PII Trimer

[Image: see text] PII proteins are sensors of α-ketoglutarate and adenylylate energy charge that regulate signal transduction proteins, metabolic enzymes, and permeases involved in nitrogen assimilation. Here, purified Escherichia coli PII and two of its receptors, ATase and NRII, were used to study...

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Detalles Bibliográficos
Autores principales: Jiang, Peng, Ninfa, Alexander J.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786245/
https://www.ncbi.nlm.nih.gov/pubmed/19877670
http://dx.doi.org/10.1021/bi9011594