Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding

BACKGROUND: This study was designed to evaluate the effect of recombinant human thrombin (rThrombin) concentration on time to hemostasis (TTH), clot durability, and clot strength in settings that replicate the heparinization and platelet inhibition often found in surgical populations. METHODS: A mod...

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Detalles Bibliográficos
Autores principales: Hughes, Steven D, Bishop, Paul D, Garcia, Richard, Zhang, Tracy, Alexander, W Allan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786906/
https://www.ncbi.nlm.nih.gov/pubmed/19925675
http://dx.doi.org/10.1186/1750-1164-3-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786906/
https://www.ncbi.nlm.nih.gov/pubmed/19925675
http://dx.doi.org/10.1186/1750-1164-3-14

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