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A Macaque Model to Study Vaginal HSV-2/Immunodeficiency Virus Co-Infection and the Impact of HSV-2 on Microbicide Efficacy

BACKGROUND: Herpes simplex virus type-2 (HSV-2) infection enhances the transmission and acquisition of human immunodeficiency virus (HIV). This occurs in symptomatic and asymptomatic stages of HSV-2 infection, suggesting that obvious herpetic lesions are not required to increase HIV spread. An anima...

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Detalles Bibliográficos
Autores principales: Crostarosa, Federica, Aravantinou, Meropi, Akpogheneta, Onome J., Jasny, Edith, Shaw, Andrew, Kenney, Jessica, Piatak, Michael, Lifson, Jeffrey D., Teitelbaum, Aaron, Hu, Lieyu, Chudolij, Anne, Zydowsky, Thomas M., Blanchard, James, Gettie, Agegnehu, Robbiani, Melissa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787245/
https://www.ncbi.nlm.nih.gov/pubmed/20011586
http://dx.doi.org/10.1371/journal.pone.0008060