Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer

INTRODUCTION: The present study compares bone morphogenetic protein (BMP)-4 and BMP-2 gene transfer as agents of chondrogenesis and hypertrophy in human primary mesenchymal stem cells (MSCs) maintained as pellet cultures. METHODS: Adenoviral vectors carrying cDNA encoding human BMP-4 (Ad.BMP-4) were...

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Detalles Bibliográficos
Autores principales: Steinert, Andre F, Proffen, Benedikt, Kunz, Manuela, Hendrich, Christian, Ghivizzani, Steven C, Nöth, Ulrich, Rethwilm, Axel, Eulert, Jochen, Evans, Christopher H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787261/
https://www.ncbi.nlm.nih.gov/pubmed/19799789
http://dx.doi.org/10.1186/ar2822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787261/
https://www.ncbi.nlm.nih.gov/pubmed/19799789
http://dx.doi.org/10.1186/ar2822

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