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Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis

INTRODUCTION: In this article, we present a comparative immunohistochemical evaluation of four clinical-stage antibodies (L19, F16, G11 and F8) directed against splice isoforms of fibronectin and of tenascin-C for their ability to stain synovial tissue alterations in rheumatoid arthritis patients. F...

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Detalles Bibliográficos
Autores principales: Schwager, Kathrin, Kaspar, Manuela, Bootz, Frank, Marcolongo, Roberto, Paresce, Erberto, Neri, Dario, Trachsel, Eveline
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787264/
https://www.ncbi.nlm.nih.gov/pubmed/19781067
http://dx.doi.org/10.1186/ar2814