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Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis

INTRODUCTION: Accumulation of B cells in the rheumatoid arthritis (RA) synovium has been reported, and it has been thought that these cells might contribute to the pathogenesis of RA by antigen presentation, autoantibody production, and/or inflammatory cytokine production. Chemokines could enhance t...

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Detalles Bibliográficos
Autores principales: Nanki, Toshihiro, Takada, Kazuki, Komano, Yukiko, Morio, Tomohiro, Kanegane, Hirokazu, Nakajima, Atsuo, Lipsky, Peter E, Miyasaka, Nobuyuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787286/
https://www.ncbi.nlm.nih.gov/pubmed/19804625
http://dx.doi.org/10.1186/ar2823