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Advanced glycation end products induce cell cycle arrest and proinflammatory changes in osteoarthritic fibroblast-like synovial cells

INTRODUCTION: Advanced glycation end products (AGEs) have been introduced to be involved in the pathogenesis of osteoarthritis (OA). The influence of AGEs on osteoarthritic fibroblast-like synovial cells (FLS) has been incompletely understood as yet. The present study investigates a potential influe...

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Detalles Bibliográficos
Autores principales: Franke, Sybille, Sommer, Manfred, Rüster, Christiane, Bondeva, Tzvetanka, Marticke, Julia, Hofmann, Gunther, Hein, Gert, Wolf, Gunter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787298/
https://www.ncbi.nlm.nih.gov/pubmed/19735566
http://dx.doi.org/10.1186/ar2807