Rab39a Binds Caspase-1 and Is Required for Caspase-1-dependent Interleukin-1β Secretion

Interleukin-1β (IL-1β) is an important pro-inflammatory cytokine that is secreted by unconventional means in a caspase-1-dependent manner. Using a one-step immunoprecipitation approach to isolate endogenous caspase-1 from the monocytic THP1 cell line, we identified previously undescribed binding par...

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Detalles Bibliográficos
Autores principales: Becker, Christine E., Creagh, Emma M., O'Neill, Luke A. J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787314/
https://www.ncbi.nlm.nih.gov/pubmed/19833722
http://dx.doi.org/10.1074/jbc.M109.046102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787314/
https://www.ncbi.nlm.nih.gov/pubmed/19833722
http://dx.doi.org/10.1074/jbc.M109.046102

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