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Rab39a Binds Caspase-1 and Is Required for Caspase-1-dependent Interleukin-1β Secretion

Interleukin-1β (IL-1β) is an important pro-inflammatory cytokine that is secreted by unconventional means in a caspase-1-dependent manner. Using a one-step immunoprecipitation approach to isolate endogenous caspase-1 from the monocytic THP1 cell line, we identified previously undescribed binding par...

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Detalles Bibliográficos
Autores principales:	Becker, Christine E., Creagh, Emma M., O'Neill, Luke A. J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Mechanisms of Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787314/ https://www.ncbi.nlm.nih.gov/pubmed/19833722 http://dx.doi.org/10.1074/jbc.M109.046102

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