Cargando…

Dual effects of TGF-β on ERα-mediated estrogenic transcriptional activity in breast cancer

BACKGROUND: TGF-β resistance often develops in breast cancer cells that in turn overproduce this cytokine to create a local immunosuppressive environment that fosters tumor growth and exacerbates the invasive and metastatic behavior of the tumor cells themselves. Smads-mediated cross-talk with the e...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Yongsheng, Wu, Liyu, Frost, Andra R, Grizzle, William, Cao, Xu, Wan, Mei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787496/
https://www.ncbi.nlm.nih.gov/pubmed/19943940
http://dx.doi.org/10.1186/1476-4598-8-111