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Dual effects of TGF-β on ERα-mediated estrogenic transcriptional activity in breast cancer
BACKGROUND: TGF-β resistance often develops in breast cancer cells that in turn overproduce this cytokine to create a local immunosuppressive environment that fosters tumor growth and exacerbates the invasive and metastatic behavior of the tumor cells themselves. Smads-mediated cross-talk with the e...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787496/ https://www.ncbi.nlm.nih.gov/pubmed/19943940 http://dx.doi.org/10.1186/1476-4598-8-111 |