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Dual effects of TGF-β on ERα-mediated estrogenic transcriptional activity in breast cancer

BACKGROUND: TGF-β resistance often develops in breast cancer cells that in turn overproduce this cytokine to create a local immunosuppressive environment that fosters tumor growth and exacerbates the invasive and metastatic behavior of the tumor cells themselves. Smads-mediated cross-talk with the e...

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Detalles Bibliográficos
Autores principales:	Ren, Yongsheng, Wu, Liyu, Frost, Andra R, Grizzle, William, Cao, Xu, Wan, Mei
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787496/ https://www.ncbi.nlm.nih.gov/pubmed/19943940 http://dx.doi.org/10.1186/1476-4598-8-111

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