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Ets-2 and p53 mediate cAMP-induced MMP-2 expression, activity and trophoblast invasion
BACKGROUND: We have previously shown that Matrix metalloproteinase (MMP) -2 is a key-enzyme in early trophoblast invasion and that Protein Kinase A (PKA) increases MMP-2 expression and trophoblast invasion. The aim of this study was to examine MMP -2 regulation by PKA in invasive trophoblasts: JAR c...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787504/ https://www.ncbi.nlm.nih.gov/pubmed/19939245 http://dx.doi.org/10.1186/1477-7827-7-135 |