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Ets-2 and p53 mediate cAMP-induced MMP-2 expression, activity and trophoblast invasion

BACKGROUND: We have previously shown that Matrix metalloproteinase (MMP) -2 is a key-enzyme in early trophoblast invasion and that Protein Kinase A (PKA) increases MMP-2 expression and trophoblast invasion. The aim of this study was to examine MMP -2 regulation by PKA in invasive trophoblasts: JAR c...

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Detalles Bibliográficos
Autores principales: Staun-Ram, Elsebeth, Goldman, Shlomit, Shalev, Eliezer
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787504/
https://www.ncbi.nlm.nih.gov/pubmed/19939245
http://dx.doi.org/10.1186/1477-7827-7-135