Loss of a single N-linked glycan from the hemagglutinin of influenza virus is associated with resistance to collectins and increased virulence in mice

BACKGROUND: Glycosylation on the globular head of the hemagglutinin (HA) protein of influenza virus acts as an important target for recognition and destruction of virus by innate immune proteins of the collectin family. This, in turn, modulates the virulence of different viruses for mice. The role o...

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Detalles Bibliográficos
Autores principales: Reading, Patrick C, Pickett, Danielle L, Tate, Michelle D, Whitney, Paul G, Job, Emma R, Brooks, Andrew G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787511/
https://www.ncbi.nlm.nih.gov/pubmed/19930664
http://dx.doi.org/10.1186/1465-9921-10-117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787511/
https://www.ncbi.nlm.nih.gov/pubmed/19930664
http://dx.doi.org/10.1186/1465-9921-10-117

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