Cargando…

Thyroid hormone receptor (TR) mutants implicated in human hepatocellular carcinoma display an altered target gene repertoire

Thyroid hormone receptors (TRs) are hormone-regulated transcription factors that control multiple aspects of normal physiology and development. Mutations in TRs have been identified at high frequency in certain cancers, including human hepatocellular carcinomas (HCCs). The majority of HCC TR mutants...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Ivan H., Privalsky, Martin L.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787677/
https://www.ncbi.nlm.nih.gov/pubmed/19749797
http://dx.doi.org/10.1038/onc.2009.265