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Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?
The structural basis for nucleotide incorporation fidelity remains an open question for all nucleic acid polymerases. Addressing this question for the viral RNA-dependent RNA polymerase (RdRp) is of particular, practical significance because it is a determinant of sensitivity to antiviral nucleoside...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787719/ https://www.ncbi.nlm.nih.gov/pubmed/19910183 http://dx.doi.org/10.1016/j.sbi.2009.10.012 |