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Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?

The structural basis for nucleotide incorporation fidelity remains an open question for all nucleic acid polymerases. Addressing this question for the viral RNA-dependent RNA polymerase (RdRp) is of particular, practical significance because it is a determinant of sensitivity to antiviral nucleoside...

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Detalles Bibliográficos
Autores principales: Cameron, Craig E, Moustafa, Ibrahim M, Arnold, Jamie J
Formato: Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787719/
https://www.ncbi.nlm.nih.gov/pubmed/19910183
http://dx.doi.org/10.1016/j.sbi.2009.10.012