A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

Severe acute respiratory syndrome (SARS) is a highly lethal emerging disease caused by coronavirus SARS-CoV. New lethal animal models for SARS were needed to facilitate antiviral research. We adapted and characterized a new strain of SARS-CoV (strain v2163) that was highly lethal in 5- to 6-week-old...

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Detalles Bibliográficos
Autores principales: Day, Craig W., Baric, Ralph, Cai, Sui Xiong, Frieman, Matt, Kumaki, Yohichi, Morrey, John D., Smee, Donald F., Barnard, Dale L.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. Published by Elsevier Inc. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787736/
https://www.ncbi.nlm.nih.gov/pubmed/19853271
http://dx.doi.org/10.1016/j.virol.2009.09.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787736/
https://www.ncbi.nlm.nih.gov/pubmed/19853271
http://dx.doi.org/10.1016/j.virol.2009.09.023

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