Cargando…

Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress

Hyperinsulinemia associated with type II diabetes mellitus is a risk factor for non-alcoholic steatohepatitis (NASH) and hepatic fibrosis. Hepatic stellate cells (HSCs) are the major effectors in collagen production during hepatic fibrogenesis. Elevated levels of insulin stimulate HSC activation. In...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Jianguo, Zheng, Shizhong, Chen, Anping
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787823/
https://www.ncbi.nlm.nih.gov/pubmed/19841616
http://dx.doi.org/10.1038/labinvest.2009.115