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The NF-κB/AKT-dependent Induction of Wnt Signaling in Colon Cancer Cells by Macrophages and IL-1β

Progression of colon cancer from microadenoma to macroscopic tumors is coupled to augmentation of canonical Wnt signaling. We recently reported that tumor associated macrophages, through interleukin 1β (IL-1β) dependent phosphorylation of GSK3β, promote Wnt signaling in colon cancer cells, demonstra...

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Detalles Bibliográficos
Autores principales: Kaler, Pawan, Godasi, Bramara N., Augenlicht, Leonard, Klampfer, Lidija
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787930/
https://www.ncbi.nlm.nih.gov/pubmed/19779850
http://dx.doi.org/10.1007/s12307-009-0030-y