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Activation of native TRPC1/C5/C6 channels by endothelin-1 is mediated by both PIP(3) and PIP(2) in rabbit coronary artery myocytes

We investigate activation mechanisms of native TRPC1/C5/C6 channels (termed TRPC1 channels) by stimulation of endothelin-1 (ET-1) receptor subtypes in freshly dispersed rabbit coronary artery myocytes using single channel recording and immunoprecipitation techniques. ET-1 evoked non-selective cation...

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Detalles Bibliográficos
Autores principales: Saleh, Sohag N, Albert, Anthony P, Large, William A
Formato: Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788089/
https://www.ncbi.nlm.nih.gov/pubmed/19770190
http://dx.doi.org/10.1113/jphysiol.2009.180331