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Strong Evidence of a Combination Polymorphism of the Tyrosine Kinase 2 Gene and the Signal Transducer and Activator of Transcription 3 Gene as a DNA-Based Biomarker for Susceptibility to Crohn’s Disease in the Japanese Population

OBJECTIVE: An association between susceptibility to inflammatory bowel disease (IBD) and polymorphisms of both the tyrosine kinase 2 gene (TYK2) and the signal transducer and activator of transcription 3 gene (STAT3) was examined in a Japanese population in order to identify the genetic determinants...

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Detalles Bibliográficos
Autores principales: Sato, Kayoko, Shiota, Mizuho, Fukuda, Sayaka, Iwamoto, Eiko, Machida, Haruhisa, Inamine, Tatsuo, Kondo, Shinji, Yanagihara, Katsunori, Isomoto, Hajime, Mizuta, Yohei, Kohno, Shigeru, Tsukamoto, Kazuhiro
Formato: Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788098/
https://www.ncbi.nlm.nih.gov/pubmed/19653082
http://dx.doi.org/10.1007/s10875-009-9320-x