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In vitro inhibition of 10-formyltetrahydrofolate dehydrogenase activity by acetaldehyde

Alcoholism has been associated with folate deficiency in humans and laboratory animals. Previous study showed that ethanol feeding reduces the dehydrogenase and hydrolase activity of 10-formyltetrahydrofolate dehydrogenase (FDH) in rat liver. Hepatic ethanol metabolism generates acetaldehyde and ace...

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Detalles Bibliográficos
Autores principales: Mun, Ju-Ae, Doh, Eunjin, Min, Hyesun
Formato: Texto
Lenguaje:English
Publicado: The Korean Nutrition Society and The Korean Society of Community Nutrition 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788200/
https://www.ncbi.nlm.nih.gov/pubmed/20016718
http://dx.doi.org/10.4162/nrp.2008.2.4.195