Cardiac Glycosides Induce Cell Death in Human Cells by Inhibiting General Protein Synthesis

BACKGROUND: Cardiac glycosides are Na(+)/K(+)-pump inhibitors widely used to treat heart failure. They are also highly cytotoxic, and studies have suggested specific anti-tumor activity leading to current clinical trials in cancer patients. However, a definitive demonstration of this putative anti-c...

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Detalles Bibliográficos
Autores principales: Perne, Andrea, Muellner, Markus K., Steinrueck, Magdalena, Craig-Mueller, Nils, Mayerhofer, Julia, Schwarzinger, Ilse, Sloane, Mathew, Uras, Iris Z., Hoermann, Gregor, Nijman, Sebastian M. B., Mayerhofer, Matthias
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788214/
https://www.ncbi.nlm.nih.gov/pubmed/20016840
http://dx.doi.org/10.1371/journal.pone.0008292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788214/
https://www.ncbi.nlm.nih.gov/pubmed/20016840
http://dx.doi.org/10.1371/journal.pone.0008292

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