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Cardiac Glycosides Induce Cell Death in Human Cells by Inhibiting General Protein Synthesis
BACKGROUND: Cardiac glycosides are Na(+)/K(+)-pump inhibitors widely used to treat heart failure. They are also highly cytotoxic, and studies have suggested specific anti-tumor activity leading to current clinical trials in cancer patients. However, a definitive demonstration of this putative anti-c...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788214/ https://www.ncbi.nlm.nih.gov/pubmed/20016840 http://dx.doi.org/10.1371/journal.pone.0008292 |