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Immunological Memory Transferred with CD4 T Cells Specific for Tuberculosis Antigens Ag85B-TB10.4: Persisting Antigen Enhances Protection

BACKGROUND: High levels of death and morbidity worldwide caused by tuberculosis has stimulated efforts to develop a new vaccine to replace BCG. A number of Mycobacterium tuberculosis (Mtb)-specific antigens have been synthesised as recombinant subunit vaccines for clinical evaluation. Recently a fus...

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Detalles Bibliográficos
Autores principales: Duffy, Darragh, Dawoodji, Amina, Agger, Else Marie, Andersen, Peter, Westermann, Jürgen, Bell, Eric B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788218/
https://www.ncbi.nlm.nih.gov/pubmed/20011592
http://dx.doi.org/10.1371/journal.pone.0008272